Left tackle Joe Staley knows the eardrum-rattling peril that awaits the 49ers in Saturday's visit to Seattle's CenturyLink Field.
"It's the loudest stadium in the NFL, so it's very difficult to play there," Staley said Wednesday. "It so loud, and you can't hear anything. Huge home-field advantage."
No stadium has had more false-start penalties by opponents since 2005 (110 in 55 games). The 49ers had only one such penalty in last season's opener in Seattle but still fell 31-6.
"It's a unique environment going up there," 49ers quarterback Alex Smith said. "Obviously we play there every year, but it's still something ... another thing we're going to have to overcome."
Saturday's five projected starting linemen have combined for 13 false-start penalties this season, including six on Staley and three on right tackle Anthony Davis. The solution for Saturday's earache: preparation.
"When you get jumpy, you're unsure of adjustments and start forgetting snap counts," Staley said. "You can quiet that nervousness by preparing during the week."
Although the line has had mixed results, technique issues and miscommunication often have been their downfall, rather than lack of discipline. The 49ers did not allow a sack in Monday night's 20-3 win over the Pittsburgh Steelers. Only six holding penalties have been called on 49ers linemen, including three on left guard Mike Iupati.