SAN FRANCISCO -- Safety Eric Reid has sustained the second concussion of his rookie season, forcing him out of the 49ers' game Sunday against the Carolina Panthers.

Reid got hurt making a third-quarter tackle of 245-pound fullback Mike Tolbert, who stayed at Reid's side as 49ers medical staff tended to him. Reid stayed down for some five minutes before he walked off the field with trainers.

Reid, the 49ers' first-round draft pick out of LSU, has started every game this season. He got knocked out of a Week 2 loss at Seattle with a concussion. Reid said earlier this season he didn't sustain any concussions in his four years at LSU.

Reid was the second player the 49ers lost to a concussion, following Vernon Davis' second-quarter lead.

Other 49ers who have sustained injuries in this game include left guard Mike Iupati (left knee), defensive tackle Ray McDonald (ankle) and tight end Garrett Celek (hamstring). Iupati did not miss a snap after getting hurt on a play in which Kendall Hunter fumbled.

For more on the 49ers, see Cam Inman's Hot Read blog at blogs.mercurynews.com/49ers. Follow him on Twitter at twitter.com/CamInman.



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