One mammoth upset wasn't enough for Shoni Schimmel and plucky Louisville. Going through two of the sport's powers, the Cardinals are Final Four bound.

Schimmel scored 24 points, and Louisville beat second-seeded Tennessee 86-78 on Tuesday night for the Oklahoma City Regional championship to earn the school's second trip to the Final Four.

Next up is a Sunday showdown in New Orleans against Cal (32-3).

Two nights after taking down Brittney Griner and defending national champion Baylor, the fifth-seeded Cardinals (28-8) built a 20-point lead and then withstood a second-half comeback by the powerhouse Lady Vols (27-8) before celebrating another big victory.

When it was over, the Cardinals huddled at center court and celebrated. Tennessee headed home with a third straight loss in the regional finals.

"We ruined the entire party," Louisville coach Jeff Walz said. " ... No one gave us a chance, and we shocked everybody."

Notre Dame 87, Duke 76: Skylar Diggins shook off early foul trouble to score 24 points, and the Irish rallied to win the Norfolk (Va.) Regional title and earn their third consecutive trip to the Final Four. They have lost in the past two national title games.

"I want to win a championship for coach (Muffet) McGraw bad," Diggins said.

The Fighting Irish (35-1) won their school-record 30th consecutive game and will play Connecticut in the Final Four for the third straight year. The Irish won the first two and have won seven of the past eight meetings.

Notre Dame swept UConn this season, winning in overtime and by 1 and 2 points.

The Irish had to rally past Duke (33-3) to get there. Trailing by six at the half, Notre Dame took control with a 15-2 run early in the second half to take a 50-42 lead.