The fight and fatal crash occurred around 3 a.m. in the 4200 block of Leimert Boulevard, said Officer Norma Eisenman of the Los Angeles Police Department.
"The altercation they were having ended up out on the street somehow," Eisenman said. "They were both struck by a vehicle."
Eisenman said both women were pronounced dead at the scene.
"It was not a hit and run," Eisenman said.
An investigation was underway to determine the circumstances of the fight and whether there was any foul play.