This was the sixth time Williams, 51, has been nominated for the prize. Nobel prizes are also awarded for achievements in physics, chemistry, physiology or medicine, and literature.
It's the fifth time Notre Dame de Namur philosophy professor Philip Gasper has nominated Williams, who is scheduled to be executed at 12:01 a.m. on Tuesday for four robberyrelated murders committed in 1979.
Surrounded Wednesday by anti-death-penalty advocates, Williams supporters and media cameras in the university's quad, Gasper announced that he was nominating Williams for the Nobel Peace Prize again because of his international work to end youth gang violence and crime.
"Mr. Williams voice has credibility with young people," Gasper said.
While in prison, Williams, who co-founded the Crips gang in Los Angeles, has become an advocate for non-violence and has written nine children's books, all of which have an anti-gang message. He has also spoken with school children, teachers, juvenile offenders, gang members and school principals about ending gang violence.
Thirty-two other professors across the nation are co-sponsoring the Nobel Peace Prize nomination.
"This is one of the clear cases that someone would make a positive contribution if they were allowed to continue to live," Gasper said.
Critics say Williams is responsible for brutal murders that changed families' lives and he should not receive mercy.
Williams, who has lost all appeal attempts, has claimed he is innocent of the shooting murders of a convenience-store clerk and two motel owners and their daughter.
"Mr. Williams has always maintained his innocence and the evidence against him is weak," Gasper said. "The man we're talking about today is a very different man than the one that went to prison."
The scheduled execution of Williams has put capital punishment in the spotlight for San Mateo County officials.
The most recent execution took place in January, when Donald Beardslee was put to death for the 1981 murder of a San Mateo County woman.
According to Deputy District Attorney Steve Wagstaffe, Beardslee's bid for clemency was handled quite differently than Williams' case.
Wagstaffe said the a state parole board, rather than the governor, held the clemency hearing, and ultimately decided to reject Beardslee's request.
A private clemency hearing led by the governor is an "interesting approach," he said.
"Having tried death penalty cases as a prosecutor, I know what it takes to get a jury to return a verdict of death," Wagstaffe said. "I'm convinced that if there were a flaw in the case, it would have been found" by the 9th U.S. Circuit Court of Appeals.
The San Mateo County Board of Supervisors, along with other Bay Area counties and cities, passed a resolution supporting a moratorium on the death penalty.
Wagstaffe said he does not support the proposed moratorium because every resource has been made available to both prosecutors and defense attorneys in the state to try a case fairly.
"The system that existed in 1979 (the year Williams was arrested) is the same as today's," he said. "The law hasn't changed."
Wire services contributed to this story.