SAN JOSE -- A 50-year-old man was arrested in San Jose on Sunday in connection with the shooting of a San Francisco police officer that later led to a multi-county chase.

The pursuit ended after CHP officers threw down a spiked strip on southbound Interstate 680 near the Berryessa and Hostetter Road intersection and punctured the fleeing Mercedes' tires, CHP Officer Chris Falkowski said.

Jeffrey Ruano, of San Francisco, was arrested on suspicion of assault with a deadly weapon, being a felon in possession of ammunition, driving in excess of 100 mph, evading police officers and a misdemeanor warrant, police said. Two women were in the car with Ruano during the pursuit, which spanned four counties and ended without incident at McKee Road and North 33rd Street in San Jose. The women were questioned and released.

San Francisco police Officer Adam Shaw, 28, underwent surgery for a shoulder wound and is expected to recover.

According to San Francisco police Officer Gordon Shyy, Ruano's car was the weapon referred to in the assault arrest, which made no mention of the discharge of a firearm.

Shyy gave the following account:

About 2:45 p.m. Saturday, San Francisco police responded to a report of malicious activity in the 1300 block of Florida Street. After police pulled over a Ford Mustang, the driver began to back up toward officers and Shaw was hit by gunfire. Another officer fired at the car, a Ford Mustang, and shattered the glass in a window.

Police believe the bullet that wounded Shaw was fired by Ruano.

Shyy said an independent witness on Florida Street heard a gunshot from the suspect's vehicle.

The Mustang fled the scene and was found later Saturday abandoned in Daly City. Officers unsuccessfully searched neighborhoods near Serramonte Center for five hours for the gunman and the car's occupants.

Later in the evening, police investigators located a white Mercedes that they believed was associated with the shooting. San Francisco officers followed the car as it traveled to the East Bay about 11 p.m.. As the car continued onto eastbound Interstate 80 in Richmond, police requested CHP help.

When CHP officers tried to stop the Mercedes near Carlson Boulevard, the driver of the car refused to pull over, Shyy said. The CHP pursued the car on eastbound 880 then south on Interstate 680, through Contra Costa, Solano, Alameda and Santa Clara counties.

The chase proceeded with sirens blaring and lights flashing at speeds ranging from 80 mph to 100 mph, CHP Officer Daniel Hill said.

In San Jose, CHP officers threw a spiked strip across the freeway and disabled the car, which exited the freeway and eventually stopped. Officers held the driver and two occupants until San Francisco police arrived.

Anyone with information about the incident may contact the San Francisco police anonymous tip line at 415-575-4444.

Contact Erin Ivie at eivie@bayareanewsgroup.com. Contact Sharon Noguchi at snoguchi@mercurynews.com or 408-271-3775.