DENVER — Matt Cain was removed in the fourth inning of Wednesday night's game against the Colorado Rockies with a right hamstring strain.
Cain had pitched three hitless innings, allowing just one base runner. He hit Justin Morneau with a fastball in the second inning but otherwise was sharp, throwing 24 of 36 pitches for strikes and getting three strikeouts looking.
Cain looked uncomfortable as he walked back to the dugout at the end of the third, and he had a long conversation with trainer Dave Groeschner, who informed manager Bruce Bochy that a change needed to be made. Long reliever Yusmeiro Petit took the mound in the bottom of the fourth.
Cain has been on the disabled list just twice in his career, both in the last two seasons. He suffered a right forearm contusion when he was hit by a line drive last August, and missed two starts earlier this season after slicing his right index finger while cutting a ham and cheese sandwich.
Giants (Tim Hudson 4-2) at Colorado (Jorge De La Rosa 5-3, 12:10 p.m., CSNBA