Seth Curry scored 19 of his 22 points in the first half as No. 6 Duke opened a 20-point lead and sent host Virginia Tech to its ninth consecutive loss, 88-56 on Thursday night.
Rasheed Sulaimon added 17 points and Mason Plumlee had 13 points and 12 rebounds for the Blue Devils (23-3, 10-3 Atlantic Coast Conference) as they moved coach Mike Krzyzewski into sole possession of third place on the career list for victories at one school with 877.
He was tied with Adolph Rupp of Kentucky and is now two behind North Carolina's Dean Smith. Syracuse's Jim Boeheim leads with 910 victories.
Erick Green, the nation's leading scorer with a 25.3 average coming in, led the Hokies (11-15, 2-11) with 22 points. C.J. Barksdale had a career-best 14 points and Cadarian Raines added 10, but no one else scored more than five as the Hokies shot just 43 percent and made only 1 of 16 3-point attempts.
Duke, meantime, buried the Hokies quickly with a 3-point barrage.
Curry had three 3s and Quinn Cook and Sulaimon also connected in an early 19-6 run, and after the teams swapped baskets, Curry capped a 15-3 burst for Duke with his fourth 3-pointer of the half.
That made the score 37-17 after 16
USF 61, Loyola Marymount 59: Cody Doolin's layup with 0.5 seconds left thwarted a second-half rally and gave the visiting Dons a win over Loyola Marymount. USF (12-15, 5-9 West Coast) led by as many as 20 in the first half, but the Lions (8-19, 1-13) came back after halftime.
USF's Cole Dickerson tied the game on a 3-pointer with a minute to play before Doolin's heroics sent the Lions to their 11th consecutive loss. Dickerson scored 16 and Doolin had 13 for USF.
Colorado 60, Utah 50: Spencer Dinwiddie scored 13 points and had a key block in the late going, helping host Colorado (18-8, 8-6 Pac-12) pull away for a victory over Utah (11-15, 3-11 Pac-12).
Tennessee 83, Auburn 61: Meighan Simmons scored 24 points and Cierra Burdick had a double-double as No. 11 the Lady Volunteers (21-5, 12-1 Southeastern Conference) trounced visiting Auburn (14-12, 3-10) to remain in sole possession of first place in the Southeastern Conference.
Simmons had 11 points in the first 8 minutes and made three 3-pointers in a 67-second span early in the game. Tra'Cee Tanner scored 20 points for Auburn.
Gonzaga 70, Santa Clara 55: Ruta Zurauskyte recorded her fifth double-double of the season (19 points, 11 rebounds) and Meagan Fulps scored 15 points, but the host Broncos (13-13, 5-8 WCC) fell to the Bulldogs (23-5, 13-1).
Santa Clara's Raquel Avila had seven assists, tying her career high. Taelor Karr led Gonzaga with 27 points.
San Diego 67, Saint Mary's 50: The Gaels (17-8, 9-4 WCC) led 23-22 at halftime but fell to San Diego's (18-8, 10-4) second-half charge. Jackie Nared had 16 points and seven rebounds for Saint Mary's.