While Alex Rodriguez remained intent on evading baseball's most sweeping punishment since the Black Sox scandal, the 12 other players accepted their suspensions for their relationship to the Biogenesis anti-aging clinic in Florida.
Rodriguez, the New York Yankees third baseman, said he will appeal his 211-game suspension by Major League Baseball. But three All-Stars -- Texas Rangers outfielder Nelson Cruz, Detroit Tigers shortstop Jhonny Peralta and San Diego Padres shortstop Everth Cabrera -- were among 12 players who accepted 50-game suspensions.
The others who accepted 50-game bans were Yankees catcher Francisco Cervelli and outfielder Fernando Martinez; Philadelphia pitcher Antonio Bastardo; Seattle catcher Jesus Montero; New York Mets infielder Jordany Valdespin and outfielder Cesar Puello; Houston pitcher Sergio Escalona; and free-agent pitchers Fautino De Los Santos and Jordan Norberto.
"Obviously, it's a big day and it's one of the days to be marked in baseball history -- a monumental day," St. Louis Cardinals manager Mike Matheny said. "I think overall the guys are happy to see it kind of come to a head, be talked about today and get it over with, and just keep playing."
The suspensions are thought to be the most at once for off-field conduct since 1921, when commissioner Kenesaw Mountain Landis banned eight Chicago White Sox players for life for throwing the 1919 World Series against Cincinnati.
As for the modern-day All-Stars, Cruz leads Texas in RBIs and Peralta has been a top hitter for Detroit, two teams in pennant races. They will be eligible to return for the postseason.
"Who knows how it is going to hurt them with Peralta and Cruz being out? Who knows who comes up and how they'll do? We'll see how it shakes up," Kansas City pitcher Aaron Crow said.
Crow has a rooting interest. The Royals could wind up chasing both affected teams -- Detroit in the division, Texas for a wild-card spot.
MLB's investigation began last year after Giants outfielder Melky Cabrera, now with Toronto, tested positive for elevated testosterone, as did A's pitcher Bartolo Colon and San Diego catcher Yasmani Grandal. All three have served their suspensions and will not receive additional discipline.
The probe escalated in January when the Miami New Times published documents obtained from former Biogenesis associate Porter Fisher that linked several players to Biogenesis.
Washington Nationals pitcher Gio Gonzalez, who was linked to Biogenesis in a newspaper report, was formally cleared by Major League Baseball.
The former A's left-hander called the report "a lie" from the start but said Monday that he has "no lingering sense of animosity" over being connected to the drug investigation.